1-Deoxynojirimycin , 10mMinDMSO , 19130-96-2
Synonym(s):
1,5-Dideoxy-1,5-imino-D -sorbitol;DNM;DNM1
CAS NO.:19130-96-2
Empirical Formula: C6H13NO4
Molecular Weight: 163.17
MDL number: MFCD00063474
EINECS: 606-239-2
Pack Size | Price | Stock | Quantity |
1ml | RMB159.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 195-196°C |
Boiling point: | 361.1±42.0 °C(Predicted) |
Density | 1.456±0.06 g/cm3(Predicted) |
vapor pressure | 0Pa at 25℃ |
RTECS | TN4350300 |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | Soluble in Water up to 25 mg/ml). |
pka | 13.77±0.70(Predicted) |
form | Powder |
color | White |
Water Solubility | Soluble in water, dimethyl sulfoxide and methanol. |
BRN | 3588039 |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months. |
LogP | -1.8 |
CAS DataBase Reference | 19130-96-2(CAS DataBase Reference) |
Description and Uses
Deoxynojirimycin (19130-96-2) inhibits α-glucosidase I and II.1,2 Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step.3 May be used to produce an affinity ligand for purifying glucosidase 1.4 Deoxynojirimycin was used to inhibit ER glucosidases I and II allowing for the discovery of a second mechanism for deglucosylation of N-linked oligosaccharides in PhaR1.7, a mouse lymphoma cell line.5
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P271-P280 |
Safety Statements | 24/25 |
WGK Germany | 1 |
HS Code | 29329990 |