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A7058658

D-pantethine , 10mMinWater , 16816-67-4

Synonym(s):
Bis(N-pantothenylamidoethyl) disulfide;LBF factor;Pantethein oxidized form

CAS NO.:16816-67-4

Empirical Formula: C22H42N4O8S2

Molecular Weight: 554.72

MDL number: MFCD07357234

EINECS: 240-842-8

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

alpha  D27 +13.5° (c = 3.75 in water)
Boiling point: 987.2±65.0 °C(Predicted)
Density  1.1949 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  2-8°C
solubility  Methanol (Slightly), Water (Slightly)
pka 12.71±0.20(Predicted)
form  syrup
color  Crystals from MeOH/Me2CO
Stability: Hygroscopic
InChIKey DJWYOLJPSHDSAL-ROUUACIJSA-N
SMILES S(CCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

Description and Uses

D-Pantethine is a compound in which two molecules of D-pantetheine bind through an S-S linkage. D-Pantethine is available from commercial sources as well as from D-pantothenic acid. It is known that the sulfhydryl group is the metabolically active part of the molecule. Coenzyme A is an essential cofactor in over 70 biological pathways, such as fatty acid oxidation, carbohydrate metabolism, and amino acid catabolism. Studies conducted in vitro suggest that D-Pantethine inhibits the activity of aldehyde dehydrogenase; however, related metabolites of the compound, such as Taurine (sc-202354), D-pantetheine, Coenzyme A, and D-pantothenate activate this enzyme.

antilipemic

Safety

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273-P391-P501
WGK Germany  3
RTECS  ES4392700
Toxicity LD50 oral in rat: > 10gm/kg

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