D-pantethine , ≥98% , 16816-67-4
Synonym(s):
Bis(N-pantothenylamidoethyl) disulfide;LBF factor;Pantethein oxidized form
CAS NO.:16816-67-4
Empirical Formula: C22H42N4O8S2
Molecular Weight: 554.72
MDL number: MFCD07357234
EINECS: 240-842-8
Pack Size | Price | Stock | Quantity |
250MG | RMB135.20 | In Stock |
|
1G | RMB367.20 | In Stock |
|
5G | RMB1279.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
alpha | D27 +13.5° (c = 3.75 in water) |
Boiling point: | 987.2±65.0 °C(Predicted) |
Density | 1.1949 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | 2-8°C |
solubility | Methanol (Slightly), Water (Slightly) |
pka | 12.71±0.20(Predicted) |
form | syrup |
color | Crystals from MeOH/Me2CO |
Stability: | Hygroscopic |
InChIKey | DJWYOLJPSHDSAL-ROUUACIJSA-N |
SMILES | S(CCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO |
Description and Uses
D-Pantethine is a compound in which two molecules of D-pantetheine bind through an S-S linkage. D-Pantethine is available from commercial sources as well as from D-pantothenic acid. It is known that the sulfhydryl group is the metabolically active part of the molecule. Coenzyme A is an essential cofactor in over 70 biological pathways, such as fatty acid oxidation, carbohydrate metabolism, and amino acid catabolism. Studies conducted in vitro suggest that D-Pantethine inhibits the activity of aldehyde dehydrogenase; however, related metabolites of the compound, such as Taurine (sc-202354), D-pantetheine, Coenzyme A, and D-pantothenate activate this enzyme.
antilipemic
Safety
Symbol(GHS) | GHS09 |
Signal word | Warning |
Hazard statements | H400 |
Precautionary statements | P273-P391-P501 |
WGK Germany | 3 |
RTECS | ES4392700 |
Toxicity | LD50 oral in rat: > 10gm/kg |