A7007158
D-(-)-Pantolactone , 10mMinDMSO , 599-04-2
Synonym(s):
(R)-(−)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone;(R)-(−)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone;(R)-(−)-Pantolactone;Pantoic acid γ-lactone
CAS NO.：599-04-2
Empirical Formula: C6H10O3
Molecular Weight: 130.14
MDL number: MFCD00005392
EINECS: 209-963-3
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 91 °C(lit.) |
| Boiling point: | 120-122 °C15 mm Hg(lit.) |
| Density | 1.1066 (rough estimate) |
| vapor pressure | 0.3-3.28Pa at 15-35℃ |
| refractive index | -50.8 ° (C=2, H2O) |
| Flash point: | 120-122°C/15mm |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly) |
| pka | 13.12±0.40(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White |
| Odor | cotton candy |
| optical activity | [α]25/D 49.8°, c = 2 in H2O |
| Water Solubility | almost transparency |
| Sensitive | Hygroscopic |
| Merck | 14,7013 |
| BRN | 80957 |
| InChIKey | SERHXTVXHNVDKA-BYPYZUCNSA-N |
| LogP | -0.973--0.46 at 22.5-25℃ and pH7.1 |
Description and Uses
D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.
It can be used as a chiral starting material to synthesize:
- An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.
- (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.
- A bicyclic diterpene named isofregenedadiol.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| Safety Statements | 22-24/25 |
| WGK Germany | 1 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29322090 |
