Home Categories Chemical Reagents D-(-)-Pantolactone
A6770612

D-(-)-Pantolactone , 99% , 599-04-2

Synonym(s):
(R)-(−)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone;(R)-(−)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone;(R)-(−)-Pantolactone;Pantoic acid γ-lactone

CAS NO.:599-04-2

Empirical Formula: C6H10O3

Molecular Weight: 130.14

MDL number: MFCD00005392

EINECS: 209-963-3

Pack Size Price Stock Quantity
5G RMB28.80 In Stock
25G RMB80.80 In Stock
100G RMB276.80 In Stock
500G RMB1100.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 91 °C(lit.)
Boiling point: 120-122 °C15 mm Hg(lit.)
Density  1.1066 (rough estimate)
vapor pressure  0.3-3.28Pa at 15-35℃
refractive index  -50.8 ° (C=2, H2O)
Flash point: 120-122°C/15mm
storage temp.  2-8°C
solubility  Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly)
pka 13.12±0.40(Predicted)
form  Crystals or Crystalline Powder
color  White
Odor cotton candy
optical activity [α]25/D 49.8°, c = 2 in H2O
Water Solubility  almost transparency
Sensitive  Hygroscopic
Merck  14,7013
BRN  80957
InChIKey SERHXTVXHNVDKA-BYPYZUCNSA-N
LogP -0.973--0.46 at 22.5-25℃ and pH7.1
CAS DataBase Reference 599-04-2(CAS DataBase Reference)
EPA Substance Registry System Pantolactone (599-04-2)

Description and Uses

D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.
It can be used as a chiral starting material to synthesize:

  • An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.
  • (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.
  • A bicyclic diterpene named isofregenedadiol.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Safety Statements  22-24/25
WGK Germany  1
3-10
TSCA  Yes
HS Code  29322090

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