Alantolactone , 10mMinDMSO , 546-43-0

Synonym(s):
(+)-Alantolactone.;3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one;Alant camphor;Elecampane camphor;Eupatal

CAS NO.：546-43-0

Empirical Formula: C15H20O2

Molecular Weight: 232.32

MDL number: MFCD00046915

EINECS: 208-899-3

PRODUCT Properties

• Melting point: 78-79 C
• Boiling point: 275 C
• alpha: D +175° (chloroform)
• Density: 1.0610 (rough estimate)
• refractive index: 1.4360 (estimate)
• storage temp.: -20°C
• solubility: DMSO: soluble15mg/mL (clear solution)
• form: powder
• color: white to beige
• Odor: Peculiar sweet-minty, slightly woody odor
• LogP: 3.380
• CAS DataBase Reference: 546-43-0(CAS DataBase Reference)

Description and Uses

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone-mix, used to detect sensitization to Compositae.

Alantolactone has been used:

• in cell viability assay
• to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
• in assessment of degranulation

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H317
• Precautionary statements: P261-P272-P280-P333+P313-P362+P364-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38-43
• Safety Statements: 26-36-36/37-24/25
• WGK Germany: 3
• HS Code: 29322090