A6945158
ExendinFragment9-39 , 10mMinDMSO , 133514-43-9
CAS NO.：133514-43-9
Empirical Formula: C149H234N40O47S
Molecular Weight: 3369.76
MDL number: MFCD02179664
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.51 |
| RTECS | LF2460000 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O : 50 mg/mL (14.84 mM; Need ultrasonic) |
| form | Solid |
| color | Off-white to pale purple |
| Water Solubility | Soluble in water at 1mg/ml |
| InChIKey | WSEVKKHALHSUMB-UHFFFAOYSA-N |
Description and Uses
Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.
Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.
Safety
| WGK Germany | 3 |
