Alendronate sodium trihydrate , 97% , 121268-17-5

Synonym(s):
4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium;Alendronate sodium trihydrate;Alendronate, Sodium Salt - CAS 121268-17-5 - Calbiochem;Alendronate, Sodium, Trihydrate, 4-Amino-1-hydroxybutylidine-1,1-bisphosphonate;MK-217

CAS NO.：121268-17-5

Empirical Formula: C4H12NO7P2.Na.3H2O

Molecular Weight: 325.12

MDL number: MFCD01748233

EINECS: 601-766-4

PRODUCT Properties

• Melting point: 245°C
• storage temp.: -20°C
• solubility: water, double-distilled: 10 mg/mL
• form: solid
• color: white
• Water Solubility: Soluble in water at 10mg/ml
• Merck: 14,229
• Stability: Store in freezer
• InChIKey: NKENDYHBVCKCNL-UHFFFAOYSA-M
• CAS DataBase Reference: 121268-17-5(CAS DataBase Reference)

Description and Uses

Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 26-36-60
• WGK Germany: 3
• RTECS: SZ6523500
• HS Code: 29310095