Phthalylsulfathiazole , >95.0%(T) , 85-73-4

Synonym(s):
PST;STP;P-PST;STP1;TSPST1

CAS NO.：85-73-4

Empirical Formula: C17H13N3O5S2

Molecular Weight: 403.43

MDL number: MFCD00005318

EINECS: 201-627-4

PRODUCT Properties

• Melting point: 198-204°C
• Boiling point: 371.31℃[at 101 325 Pa]
• Density: 1.4235 (rough estimate)
• vapor pressure: 0Pa at 25℃
• refractive index: 1.6390 (estimate)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in ethanol (96 per cent).
• pka: 3.40±0.36(Predicted)
• form: Solid
• color: White to Light Yellow
• Water Solubility: 400mg/L at 28℃
• Merck: 14,7377
• BRN: 359901
• LogP: -2 at 28℃

Description and Uses

Phthalylsulfathiazole is a sulfonamide antibacterial drug with similar and stronger effects than Sulfaguanidine and Succinylsulfathiazole. It is rarely absorbed orally and slowly decomposes in the intestine to release Sulfathiazole and exert intestinal antibacterial effects, and is used in the treatment of dysentery, colitis, and gastroenteritis.

Safety

• Symbol(GHS): GHS07,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H412
• Precautionary statements: P273-P501
• Safety Statements: 24/25
• RIDADR: 3249
• RTECS: TH8575000
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29350090
• Toxicity: LD50 i.p. in mice: 920 mg/kg (Mattis)