Home Categories Organic Chemistry 4-Aminobenzoic acid
A0661612

4-Aminobenzoic acid , Analysis standard , 150-13-0

Synonym(s):
4-Aminobenzoic acid;PABA;para-Aminobenzoic acid;Vitamin Bx;Vitamin H1

CAS NO.:150-13-0

Empirical Formula: C7H7NO2

Molecular Weight: 137.14

MDL number: MFCD00007894

EINECS: 205-753-0

Pack Size Price Stock Quantity
100MG RMB316.80 In Stock
250mg RMB639.20 In Stock
500mg RMB1023.20 In Stock
1g RMB1647.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 187-189 °C(lit.)
Boiling point: 251.96°C (rough estimate)
Density  1.374 g/mL at 25 °C(lit.)
vapor pressure  0Pa at 25℃
refractive index  1.5323 (estimate)
Flash point: 250 °C
storage temp.  2-8°C
solubility  95% ethanol: soluble5%, clear to slightly hazy, colorless to yellow
form  Crystalline Powder
pka 2.50, 4.87(at 25℃)
color  White to light yellow
PH 3.5 (5g/l, H2O, 20℃)
Odor Odorless
PH Range 3.5
Water Solubility  4.7 g/L (20 ºC)
Sensitive  Air & Light Sensitive
Merck  14,423
BRN  471605
Stability: Stable. Incompatible with strong oxidizing agents. Combustible. Sensitive to light and air. May discolour on exposure to light.
InChIKey ALYNCZNDIQEVRV-UHFFFAOYSA-N
LogP 0.96 at 25℃

Description and Uses

4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the number 4 carbon in the benzene ring is also known as the para position) is an organic compound with the formula H2NC6H4CO2H. PABA is a white solid, although commercial samples can appear gray. It is slightly soluble in water. It consists of a benzene ring substituted with amino and a carboxyl groups. The compound occurs naturally. The potassium salt is used as a drug against fibrotic skin disorders, such as Peyronie's disease, under the trade name Potaba. PABA is also occasionally used in pill form by sufferers of irritable bowel syndrome to treat its associated gastrointestinal symptoms, and in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels.

4-aminobenzoic acid is an aminobenzoic acid isomer that combines with pteridine and glutamic acid to folic acid. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in sunscreens. Also it is used as a component of some medicines e.g analgesic or anesthetic preparations sunscreen agents and bentiromide.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-43
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  DG1400000
TSCA  Yes
HS Code  29224995
Toxicity LD50 in mice, rats (g/kg): 2.85, >6.0 orally (Scott, Robbins); LD50 in rabbits (g/kg): 2.0 i.v. (Richards); 1.83 orally (Cronheim)

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