Piroxicam , ≥98%(HPLC) , 36322-90-4
Synonym(s):
4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide;Piroxicam
CAS NO.：36322-90-4
Empirical Formula: C15H13N3O4S
Molecular Weight: 331.35
MDL number: MFCD00057317
EINECS: 252-974-3
| Pack Size | Price | Stock | Quantity |
| 1G | RMB27.20 | In Stock |
|
| 5G | RMB40.80 | In Stock |
|
| 25G | RMB93.60 | In Stock |
|
| 100G | RMB271.20 | In Stock |
|
| 500g | RMB1072.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 198-200°C |
| Density | 1.3664 (rough estimate) |
| refractive index | 1.6320 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrous ethanol. It shows polymorphism (5.9). |
| pka | 6.3 (2:1 dioxane-water) |
| form | Solid |
| color | White to Light yellow |
| Water Solubility | Soluble in water, ethanol, chloroform, ethyl acetate. |
| λmax | 358nm(H2O)(lit.) |
| Merck | 14,7506 |
| BCS Class | 2 |
| InChIKey | QYSPLQLAKJAUJT-UHFFFAOYSA-N |
| CAS DataBase Reference | 36322-90-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Piroxicam(36322-90-4) |
| EPA Substance Registry System | 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide (36322-90-4) |
Description and Uses
Piroxieam is a non-steroidal anti-inflammatory drug, of the oxieam class. A contact and photocontact sensitizer, which induced contact dermatitis in a physieal therapist. Piroxieam generally cross reacts with thiosalicylic acid and also with thiomersal. Cross sensitivity is not observed to tenoxicam.
Piroxicam is used in inflammatory and degenerative diseases of the musculoskeletal system that are accompanied by painful symptoms. It is used for rheumatic heart disease, nonspecific infectious polyarthritis, gouty arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, arthrosis, back pain, neuralgia, myalgia, and other diseases associated with inflammation.
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H373 |
| Precautionary statements | P260-P264-P270-P301+P310-P314-P405 |
| Hazard Codes | Xn,F,T |
| Risk Statements | 22-25 |
| Safety Statements | 26-36 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | DL0705000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29349990 |
| Toxicity | LD50 orally in mice: 360 mg/kg (Wiseman) |
