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A0785012

Ampiroxicam , ≥98% , 99464-64-9

CAS NO.:99464-64-9

Empirical Formula: C20H21N3O7S

Molecular Weight: 447.46

MDL number: MFCD00866079

EINECS: 807-877-6

Pack Size Price Stock Quantity
50MG RMB79.20 In Stock
250MG RMB239.20 In Stock
1G RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 159-161?C
Density  1.44±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 12.74±0.20(Predicted)
color  White to Off-White
CAS DataBase Reference 99464-64-9(CAS DataBase Reference)

Description and Uses

Ampiroxicam is a once-daily non-steroidal anti-inflammatory drug (NSAID) introduced in Japan. As a non-acidic ether carbonate prodrug of the widely used antiinflammatory agent, piroxicam, ampiroxicam is similar or more potent than piroxicam in suppressing carrageenan edema, ultraviolet erythema, traumatic edema, capillary permeability, acetic acid writhing, yeast algesia and yeast hyperthermia in many animals. Eioavailability studies in man show undetectable plasma levels of ampiroxicam indicating 100% conversion to piroxicam during absorption process. Ampiroxicam has been reported to have fewer side effects on the gastric mucosa than piroxicam.

antiinflammatory, analgesic

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 orally in male, female rats: 1798, 747 mg/kg (Iijima)

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