Nimodipine , ≥98% , 66085-59-4

Synonym(s):
1,4-Dihydro-2,6-dimethyl-4-(3ʹ-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl-1-methylethyl Ester;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester;Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate;Nimodipine;Nimodipine - CAS 66085-59-4 - Calbiochem

CAS NO.：66085-59-4

Empirical Formula: C21H26N2O7

Molecular Weight: 418.44

MDL number: MFCD00153848

EINECS: 266-127-0

PRODUCT Properties

• Melting point: 125°C
• Boiling point: 536.21°C (rough estimate)
• Density: 1.3268 (rough estimate)
• refractive index: 1.6500 (estimate)
• storage temp.: 2-8°C
• solubility: methanol: 62.5 mg/mL
• form: solid
• pka: 2.77±0.70(Predicted)
• color: white
• Merck: 14,6551
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
• InChIKey: UIAGMCDKSXEBJQ-UHFFFAOYSA-N
• CAS DataBase Reference: 66085-59-4(CAS DataBase Reference)
• NIST Chemistry Reference: Nimodipine(66085-59-4)

Description and Uses

Nimodipine is a cerebral vasodilating calcium antagonist related to nifedipine. It is indicated for the prophylaxis and treatment of neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage.

provitamin, antixerophthalamic

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: Xn
• Risk Statements: 20/21/22-48/22
• Safety Statements: 36
• WGK Germany: 1
• RTECS: US7975500
• HazardClass: IRRITANT
• HS Code: 29333990
• Toxicity: LD50 in mice, rats (mg/kg): 3562, 6599 orally; 33, 16 i.v. (Schlüter)