A6201512
Nifedipine , ≥98.0%(HPLC) , 21829-25-4
Synonym(s):
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester;L-Type Calcium Channel Blocker III;Nifedipine;Nifedipine - CAS 21829-25-4 - Calbiochem
CAS NO.：21829-25-4
Empirical Formula: C17H18N2O6
Molecular Weight: 346.33
MDL number: MFCD00057326
EINECS: 244-598-3
| Pack Size | Price | Stock | Quantity |
| 5G | RMB44.00 | In Stock |
|
| 25G | RMB74.40 | In Stock |
|
| 100G | RMB202.40 | In Stock |
|
| 500G | RMB618.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 171-175 °C |
| Boiling point: | 481.08°C (rough estimate) |
| Density | 1.2109 (rough estimate) |
| refractive index | 1.5486 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | powder |
| pka | pKa -0.9/>13(DMF,t undefined) (Uncertain) |
| color | yellow |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| Merck | 14,6528 |
| BCS Class | 2 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day. |
| InChIKey | CYCWGQFQPAYBHG-UHFFFAOYSA-N |
Description and Uses
Nifedipine (21829-25-4) is a clinically useful L-type calcium blocker.
For the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 1 |
| RTECS | US7975000 |
| HazardClass | IRRITANT |
| HS Code | 29333990 |
| Toxicity | LD50 in mice, rats (mg/kg): 494, 1022 orally; 4.2, 15.5 i.v. (Vater) |
