Minoxidil , >98.0%(HPLC)(T) , 38304-91-5
Synonym(s):
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide;6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide;Minoxidil
CAS NO.：38304-91-5
Empirical Formula: C9H15N5O
Molecular Weight: 209.25
MDL number: MFCD00063409
EINECS: 253-874-2
| Pack Size | Price | Stock | Quantity |
| 1G | RMB27.20 | In Stock |
|
| 5G | RMB79.20 | In Stock |
|
| 25G | RMB221.60 | In Stock |
|
| 100G | RMB737.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 272-274 °C (dec.) (lit.) |
| Boiling point: | 348.61°C (rough estimate) |
| Density | 1.1651 (rough estimate) |
| refractive index | 1.7610 (estimate) |
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water, soluble in methanol and in propylene glycol. |
| pka | 4.61(at 25℃) |
| form | Solid |
| color | White |
| Water Solubility | Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol. |
| Merck | 14,6203 |
| BCS Class | 3 |
| Stability: | Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChIKey | ZFMITUMMTDLWHR-UHFFFAOYSA-N |
| CAS DataBase Reference | 38304-91-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Minoxidil(38304-91-5) |
Description and Uses
Minoxidil is a peripheral vasodilator that directly relaxes vascular smooth musculature, thus, lowering systolic and diastolic pressure. Its action is linked to the activation of calcium channels. Open calcium channels cause hyperpolarization of smooth muscle cells, which in turn, reduces the flow of calcium ions into the cell, which is necessary for supporting vascular tonicity. However, when taking minoxidil, tachycardia, elevated renin secretion, and water and sodium ion retention all appear simultaneously with hypotension.
A selective ATP dependent K+ (Kir6) channel activator
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P301+P312+P330-P305+P351+P338 |
| Hazard Codes | Xn,T+ |
| Risk Statements | 22-36/37/38-26/27/28 |
| Safety Statements | 26-36-45-36/37/39-22 |
| WGK Germany | 3 |
| RTECS | UV8200000 |
| HS Code | 29335990 |
| Hazardous Substances Data | 38304-91-5(Hazardous Substances Data) |
| Toxicity | LD50 in rats, mice (mg/kg): 49, 51 i.v. (Carlson, Feenstra) |
