Finasteride , >98.0% , 98319-26-7
Synonym(s):
N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide;N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide;Finasteride;MK-906
CAS NO.：98319-26-7
Empirical Formula: C23H36N2O2
Molecular Weight: 372.54
MDL number: MFCD00869737
EINECS: 620-534-3
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB87.20 | In Stock |
|
| 1G | RMB191.20 | In Stock |
|
| 5g | RMB671.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 253 °C |
| alpha | 405 -59° (c = 1 in methanol) |
| Boiling point: | 576.6±50.0 °C(Predicted) |
| Density | 1.065±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: 32 mg/mL, soluble |
| form | solid |
| pka | 14.17±0.70(Predicted) |
| color | white to beige |
| Water Solubility | insoluble |
| Merck | 14,4082 |
| BCS Class | 1 |
| InChIKey | DBEPLOCGEIEOCV-WSBQPABSSA-N |
| LogP | 3.030 |
| CAS DataBase Reference | 98319-26-7(CAS DataBase Reference) |
| EPA Substance Registry System | 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- (98319-26-7) |
Description and Uses
Finasteride, a novel 4-azasteroid, is a breakthrough in the treatment and control of benign prostatic hyperplasia. Mechanistically, it inhibits the prostatic-specific enzyme 5-alpha reductase, thereby decreasing the conversion of testosterone to dihydrotestosterone. It is reportedly effective in reducing urinary symptoms and prostatic volume and increasing maximal urinary flow rate. Finasteride is also being investigated as a treatment for prostatic cancer.
Finasteride is an antialopecia agent that Inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. It is used to treatment of benign prostatic hyperplasia and androgenetic alopecia.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302-H360FD |
| Precautionary statements | P202-P264-P270-P280-P301+P312-P308+P313 |
| Hazard Codes | Xn,T,Xi |
| Risk Statements | 22-61-60-36/37/38 |
| Safety Statements | 36/37/39-45-53-36-26-24/25 |
| WGK Germany | 3 |
| RTECS | CL5245000 |
| HS Code | 29379000 |
| Hazardous Substances Data | 98319-26-7(Hazardous Substances Data) |
