Myristicin , Analysis standard , 607-91-0

Synonym(s):
4-Methoxy-6-(2-propenyl)-1,3-benzodioxole;5-Allyl-2,3-(methylendioxy)anisole;6-Allyl-4-methoxy-1,3-benzodioxole

CAS NO.：607-91-0

Empirical Formula: C11H12O3

Molecular Weight: 192.21

MDL number: MFCD00133549

EINECS: 210-146-9

PRODUCT Properties

• Melting point: -20℃
• Boiling point: bp40 173°
• Density: d2020 1.1437
• refractive index: nD20 1.54032
• storage temp.: 2-8°C
• solubility: Soluble in acetone, ethanol and methanol
• form: oil
• color: clear, light yellow
• Odor: at 100.00 %. spicy warm balsamic woody
• Odor Type: spicy
• Water Solubility: insoluble in water
• BRN: 166218
• Stability: Light Sensitive
• LogP: 2.586 (est)

Description and Uses

Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects. Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma. This product is intended for forensic and research purposes.

A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells

Safety

• Symbol(GHS): GHS07,GHS08,GHS09
• Signal word: Warning
• Hazard statements: H302-H361f-H411
• Precautionary statements: P202-P264-P270-P273-P301+P312-P308+P313
• Risk Statements: 52/53
• Safety Statements: 61
• RIDADR: UN 3082 9/PG 3
• WGK Germany: 1
• RTECS: CY2625000
• F: 10-23
• Toxicity: A naturally occurring methylenedioxyphenyl compound found in nutmeg. It has been suggested that myristicin may be responsible, in whole or in part, for the toxicity of nutmeg. The spice (5-15 g) causes symptoms similar to atropine poisoning: flushing of the skin, tachycardia, absence of salivation, and excitation of the CNS. Euphoria and hallucinations have given rise to abuse of this material. As a methylenedioxyphenyl compound, myristicin gives rise to a type III spectrum with reduced cytochrome P450 and can inhibit monooxygenations catalyzed by this cytochrome.