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A5548712

Menaquinone 4(Mixture of cis-trans isomers) , 98%(Mixtureofcis-transisomers) , 863-61-6

Synonym(s):
Menaquinone 4;Menatetrenone

CAS NO.:863-61-6

Empirical Formula: C31H40O2

Molecular Weight: 444.65

MDL number: MFCD00079646

Pack Size Price Stock Quantity
250MG RMB295.20 In Stock
1G RMB852.80 In Stock
5g RMB2959.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 350C
Boiling point: 494.59°C (rough estimate)
Density  1.0461 (rough estimate)
refractive index  1.5045 (estimate)
Flash point: 2℃
storage temp.  -20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form  Solid
color  Light Yellow to Yellow Oil
InChIKey DKHGMERMDICWDU-GHDNBGIDSA-N

Description and Uses

Menatetrenone (also known as MK-4) is a manaquinone compound and a vitamin K compound which can be used as a hemostatic agent as well as adjunctive therapy for the pain of osteoporosis. It mainly takes effects through modulating the signaling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos. It is capable of inhibiting tumor cells growth through inducing apoptosis and cell cycle arrest. It can be produced via the conversion of vitamin K1 inside the body including the testes, pancreas and arterial walls.

Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 4 has four isoprene residue in its side chain and is also commonly refered to as menatetrenone. Menaquinone-4 is the most common type of vitamin K2 and is known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P280-P305+P351+P338
Safety Statements  22-24/25
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  QL9279500
HS Code  2914699000
Toxicity LD50 intravenous in dog: > 40mL/kg

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