Menadione , 98% , 58-27-5

Synonym(s):
2-Methyl-1,4-naphthoquinone;Menadione;MN;Vitamin K₃

CAS NO.：58-27-5

Empirical Formula: C11H8O2

Molecular Weight: 172.18

MDL number: MFCD00001681

EINECS: 200-372-6

PRODUCT Properties

• Melting point: 105-107 °C(lit.)
• Boiling point: 262.49°C (rough estimate)
• Density: 1.1153 (rough estimate)
• refractive index: 1.5500 (estimate)
• storage temp.: room temp
• solubility: oil: soluble
• form: crystalline
• color: yellow
• Odor: Slight odor
• Water Solubility: INSOLUBLE
• Sensitive: Light Sensitive
• Merck: 14,5831
• BRN: 1908453
• Stability: Stable. May be light sensitive. Incompatible with strong oxidizing agents.
• InChIKey: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• LogP: 2.200

Description and Uses

Vitamin K is a general term referring to a group of naphthoquinone derivatives required in the diet for blood clotting. Menadione is a fat-soluble vitamin that is essential for blood clotting. It is destroyed by irradiation during processing but has no appreciable loss during storage. It occurs in spinach, cabbage, liver, and wheat bran.

Menadione is precursor to verious types of Vitamin K. It is of industrial importance as an intermediate in the synthesis of phylloquinone, and salts of its bisulfite adduct are used as stabilized forms in the animal feed industry. Commercially significant forms are menadione sodium bisulfite and menadione dimethyl pyrimidinol. Used as a micronutrient for livestock and pet foods.

Safety

• Symbol(GHS): GHS07,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H302-H315-H319-H334-H335-H410
• Precautionary statements: P261-P264-P273-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38-43
• Safety Statements: 26-36-37/39-24
• WGK Germany: 3
• RTECS: QL9100000
• F: 8
• TSCA: Yes
• HazardClass: IRRITANT
• HS Code: 29147000
• Toxicity: LD50 orally in mice: ~0.5 g/kg (Molitor, Robinson)