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A5379112

Menadione , Analysis standard , 58-27-5

Synonym(s):
2-Methyl-1,4-naphthoquinone;Menadione;MN;Vitamin K3

CAS NO.:58-27-5

Empirical Formula: C11H8O2

Molecular Weight: 172.18

MDL number: MFCD00001681

EINECS: 200-372-6

Pack Size Price Stock Quantity
250MG RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 105-107 °C(lit.)
Boiling point: 262.49°C (rough estimate)
Density  1.1153 (rough estimate)
refractive index  1.5500 (estimate)
storage temp.  room temp
solubility  oil: soluble
form  crystalline
color  yellow
Odor Slight odor
Water Solubility  INSOLUBLE
Sensitive  Light Sensitive
Merck  14,5831
BRN  1908453
Stability: Stable. May be light sensitive. Incompatible with strong oxidizing agents.
InChIKey MJVAVZPDRWSRRC-UHFFFAOYSA-N
LogP 2.200
CAS DataBase Reference 58-27-5(CAS DataBase Reference)
NIST Chemistry Reference Menadione(58-27-5)
EPA Substance Registry System Menadione (58-27-5)

Description and Uses

Vitamin K is a general term referring to a group of naphthoquinone derivatives required in the diet for blood clotting. Menadione is a fat-soluble vitamin that is essential for blood clotting. It is destroyed by irradiation during processing but has no appreciable loss during storage. It occurs in spinach, cabbage, liver, and wheat bran.

Menadione is precursor to verious types of Vitamin K. It is of industrial importance as an intermediate in the synthesis of phylloquinone, and salts of its bisulfite adduct are used as stabilized forms in the animal feed industry. Commercially significant forms are menadione sodium bisulfite and menadione dimethyl pyrimidinol. Used as a micronutrient for livestock and pet foods.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H315-H319-H334-H335-H410
Precautionary statements  P261-P264-P273-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-43
Safety Statements  26-36-37/39-24
WGK Germany  3
RTECS  QL9100000
8
TSCA  Yes
HazardClass  IRRITANT
HS Code  29147000
Hazardous Substances Data 58-27-5(Hazardous Substances Data)
Toxicity LD50 orally in mice: ~0.5 g/kg (Molitor, Robinson)

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