6-Maleimidohexanoic Acid , 98%(GC) , 55750-53-3
Synonym(s):
MCA;6-Maleimidocaproic acid;Maleimidocaproic acid;N-Maleoyl-6-aminocaproic acid;2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid
CAS NO.：55750-53-3
Empirical Formula: C10H13NO4
Molecular Weight: 211.21
MDL number: MFCD00043140
EINECS: 611-311-1
| Pack Size | Price | Stock | Quantity |
| 1G | RMB31.20 | In Stock |
|
| 5G | RMB71.20 | In Stock |
|
| 25G | RMB267.20 | In Stock |
|
| 100G | RMB891.20 | In Stock |
|
| 500g | RMB3599.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 86-91 °C |
| Boiling point: | 407.3±28.0 °C(Predicted) |
| Density | 1.285±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| pka | 4.74±0.10(Predicted) |
| form | Powder |
| color | White to pale yellow |
| Water Solubility | Soluble in water, methanol, ethanol, dimethyl sulfoxide. Insoluble in ether. |
| Sensitive | Moisture Sensitive |
| BRN | 1532405 |
| InChIKey | WOJKKJKETHYEAC-UHFFFAOYSA-N |
Description and Uses
6-Maleimidocaproic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
6-Maleimidohexanoic acid is used as a probe for introducing maleimides groups into biomolecules and active pharmaceutical ingredients. Further, it is used with N-hydroxysuccinimide ester as a bifunctional cross-linking reagent. In addition to this, it acts as a probe for thiol groups in membrane proteins.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-41-37/38 |
| Safety Statements | 26-36-39 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 29251900 |
