T9686730
Phthalimide , >98.0%(GC)(T) , 85-41-6
Synonym(s):
1,3-Dihydro-1,3-dioxoisoindole;Phthalic acid imide;Phthalimide
CAS NO.：85-41-6
Empirical Formula: C8H5NO2
Molecular Weight: 147.13
MDL number: MFCD00005881
EINECS: 201-603-3
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 232-235 °C(lit.) |
| Boiling point: | 366 °C |
| Density | 1.21 |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.4700 (estimate) |
| Flash point: | 165 °C |
| storage temp. | Store below +30°C. |
| solubility | water: slightly soluble(lit.) |
| pka | 8.3(at 25℃) |
| form | Crystalline Flakes |
| color | White to slightly yellow |
| PH | 3.8 (0.6g/l, H2O) |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| Sublimation | 366 ºC |
| Merck | 14,7373 |
| BRN | 118522 |
| InChIKey | XKJCHHZQLQNZHY-UHFFFAOYSA-N |
| LogP | 1.15 |
| CAS DataBase Reference | 85-41-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Phthalimide(85-41-6) |
| EPA Substance Registry System | Phthalimide (85-41-6) |
Description and Uses
Phthalimide is a reagent used to transform allyl- and alkyl halides into protected primary amines. Phthalimide analogues have been extensively used in medicinal chemistry owing to their wide spectrum of applications as anti-convulsant, anti-inflammatory, analgesic, hypolipidimic and immunomodulatory activities. Dyes and metabolites, Environmental Testing.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Risk Statements | 20/21/22-36/37/38-40 |
| Safety Statements | 22-24/25 |
| WGK Germany | 1 |
| RTECS | TI3920000 |
| Autoignition Temperature | >500 °C |
| TSCA | Yes |
| HS Code | 29251995 |
| Hazardous Substances Data | 85-41-6(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 10000 mg/kg LD50 dermal Rabbit > 7940 mg/kg |
