A5460012
2'-O-Methyluridine , 99% , 2140-76-3
CAS NO.：2140-76-3
Empirical Formula: C10H14N2O6
Molecular Weight: 258.23
MDL number: MFCD00056054
EINECS: 2017-001-1
| Pack Size | Price | Stock | Quantity |
| 200mg | RMB68.00 | In Stock |
|
| 1G | RMB129.60 | In Stock |
|
| 5G | RMB376.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 154-156°C |
| Density | 1.53±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.39±0.10(Predicted) |
| form | Powder |
| color | White to Off-white |
| PH | ～9.3 |
| λmax | 261nm(MeOH)(lit.) |
Description and Uses
2'-O-Methyluridine is an analog of uridine and has been shown to have antiviral and anticancer properties. 2'-O-Methyluridine inhibits protein synthesis by competing with uridine for the active site of the enzyme ribonucleotide reductase, which converts ribonucleotides to dNMPs. This compound also inhibits RNA synthesis by disrupting the pairing of adenine and cytosine residues in RNA strands.
Uridine analog. 2'-O-Methyluridine is used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H311-H331 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
