PRODUCT Properties
Melting point: | 112.5-113.5° |
Boiling point: | 311.75°C (rough estimate) |
Density | 1.1305 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 11.28±0.23(Predicted) |
form | Solid |
color | Pale Beige |
CAS DataBase Reference | 54-92-2 |
Description and Uses
Iproniazid is a hydrazine based drug used as an antidepressant. Iproniazid acts as an irreversible and nonselective monoamine oxidase inhibitor.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P501-P270-P264-P301+P312+P330 |
HS Code | 2933399990 |
Toxicity | An isopropyl derivative of isoniazid that was found to have mood-elevating effects in tuberculosis patients. It was later found to be a monoamine oxidase (MAO) inhibitor and, although not currently approved for clinical use as an antidepressant due to its propensity to cause liver damage it led to the development of other MAO inhibitors currently in use. In addition to hepatotoxic effects, iproniazid is a hypotensive agent and can cause potentially hazardous reactions with other drugs and amine-rich foods. |