Procaine hydrochloride , 99% , 51-05-8

Synonym(s):
p-Aminobenzoic acid diethylaminoethyl ester hydrochloride;4-Aminobenzoic acid 2-diethylaminoethyl ester;Novocaine hydrochloride

CAS NO.：51-05-8

Empirical Formula: C13H21ClN2O2

Molecular Weight: 272.77

MDL number: MFCD00007893

EINECS: 200-077-2

PRODUCT Properties

• Melting point: 155-156 °C(lit.)
• Boiling point: 195-196°C 17mm
• Density: 1.1761 (rough estimate)
• refractive index: 1.5270 (estimate)
• Flash point: 195-196°C/17mm
• storage temp.: 2-8°C
• form: Crystals or Crystalline Powder
• color: Colorless to white
• Water Solubility: soluble
• Sensitive: Air Sensitive
• Merck: 14,7757
• BRN: 3917802
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChIKey: HCBIBCJNVBAKAB-UHFFFAOYSA-N
• LogP: 2.364 (est)

Description and Uses

Procaine hydrochloride, also called Novocain, or Novocaine, a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The above information is edited by the chemicalbook of Kui Xiongfeng.

Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H317
• Precautionary statements: P261-P264-P270-P280-P301+P310-P302+P352
• Hazard Codes: T
• Risk Statements: 25-43-36/37/38-23/24/25
• Safety Statements: 36/37/39-45-37/39-26
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: DG2275000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29242990
• Toxicity: LD50 in mice (mg/kg): 660 ± 60 s.c. (Goldenthal)