Home Categories API Procaine hydrochloride
A6726312

Procaine hydrochloride , 99% , 51-05-8

Synonym(s):
p-Aminobenzoic acid diethylaminoethyl ester hydrochloride;4-Aminobenzoic acid 2-diethylaminoethyl ester;Novocaine hydrochloride

CAS NO.:51-05-8

Empirical Formula: C13H21ClN2O2

Molecular Weight: 272.77

MDL number: MFCD00007893

EINECS: 200-077-2

Pack Size Price Stock Quantity
25G RMB43.20 In Stock
100G RMB100.00 In Stock
500G RMB295.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 155-156 °C(lit.)
Boiling point: 195-196°C 17mm
Density  1.1761 (rough estimate)
refractive index  1.5270 (estimate)
Flash point: 195-196°C/17mm
storage temp.  2-8°C
form  Crystals or Crystalline Powder
color  Colorless to white
Water Solubility  soluble
Sensitive  Air Sensitive
Merck  14,7757
BRN  3917802
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey HCBIBCJNVBAKAB-UHFFFAOYSA-N
LogP 2.364 (est)

Description and Uses

Procaine hydrochloride, also called Novocain, or Novocaine, a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The above information is edited by the chemicalbook of Kui Xiongfeng.

Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H317
Precautionary statements  P261-P264-P270-P280-P301+P310-P302+P352
Hazard Codes  T
Risk Statements  25-43-36/37/38-23/24/25
Safety Statements  36/37/39-45-37/39-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DG2275000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29242990
Toxicity LD50 in mice (mg/kg): 660 ± 60 s.c. (Goldenthal)

RELATED PRODUCTS