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A5454812

Moclobemide (Ro 111163) , 98% , 71320-77-9

Synonym(s):
4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide;Aurorix;Moclamine

CAS NO.:71320-77-9

Empirical Formula: C13H17ClN2O2

Molecular Weight: 268.74

MDL number: MFCD00865388

EINECS: 629-727-7

Pack Size Price Stock Quantity
10MG RMB228.80 In Stock
50MG RMB905.60 In Stock
100mg RMB1574.40 In Stock
250MG RMB3039.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 137°C
Boiling point: 447.7±40.0 °C(Predicted)
Density  1.206±0.06 g/cm3(Predicted)
storage temp.  room temp
solubility  DMSO: >20mg/mL
pka 14.26±0.46(Predicted)
form  solid
color  white
Merck  14,6226
CAS DataBase Reference 71320-77-9(CAS DataBase Reference)
NIST Chemistry Reference Moclobemide(71320-77-9)

Description and Uses

Moclobemide is the first of a new generation of non-hydrazine, reversible MAO-A inhibitors useful in the treatment of depression. Moclobemide is a selective inhibitor of MAO-A, allowing tyramine to be metabolized by MAO-B. In controlled studies, moclobemide was clinically superior to desipramine and showed no cholinergic or cardiovascular side-effects. A metabolite is currently under investigation for treatment of Parkinson’s disease,.

A reversible monoamine oxidase inhibitor.

Safety

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xn,T+
Risk Statements  22-37/38-41-26/27/28
Safety Statements  26-39-45-36/37/39-22
RIDADR  3249
WGK Germany  2
RTECS  CV2462000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29349990
Hazardous Substances Data 71320-77-9(Hazardous Substances Data)
Toxicity LD50 in rats (mg/kg): 707 orally (Burkard, Wyss)

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