Ionomycin (Calcium salt) , ≥98%(HPLC) , 56092-82-1
Synonym(s):
Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem
CAS NO.：56092-82-1
Empirical Formula: C41H70CaO9
Molecular Weight: 747.07
MDL number: MFCD00083634
EINECS: 617-954-4
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB479.20 | In Stock |
|
| 5MG | RMB870.40 | In Stock |
|
| 25MG | RMB3999.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 205-206 C |
| Flash point: | 87 °C |
| storage temp. | −20°C |
| solubility | Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol |
| form | White to off-white solid |
| color | white to off-white |
| biological source | Streptomyces conglobatus |
| Sensitive | Light Sensitive |
| BRN | 1416163 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
Description and Uses
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 μM. Ionomycin (5 μM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; ) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.
Ionomycin is more effectivethan A23187 as a Ca++ionophore; Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons.
