Indole-3-acetamide , 98% , 879-37-8

Synonym(s):
3-Indolylacetamide;NSC 1969

CAS NO.：879-37-8

Empirical Formula: C10H10N2O

Molecular Weight: 174.2

MDL number: MFCD00005641

EINECS: 212-904-4

PRODUCT Properties

• Melting point: 148-150 °C(lit.)
• Boiling point: 469.7±28.0 °C(Predicted)
• Density: 1.285±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMSO (Slightly)
• form: Solid
• pka: 16.37±0.40(Predicted)
• color: White to Off-White
• InChI: InChI=1S/C10H10N2O/c11-10(13)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H2,11,13)
• InChIKey: ZOAMBXDOGPRZLP-UHFFFAOYSA-N
• SMILES: N1C2=C(C=CC=C2)C(CC(N)=O)=C1

Description and Uses

Indole-3-acetamide was used in the synthesis of [5.5.6.6]diazafenestrane skeleton and indole-3-acetic acid.
Reactant for the synthesis of:
PET agent for imaging of protein kinase C
A potential agent against Prion Disease
Protein kinase C (PKC) inhibitor bisindolylmaleimide IV
Glycogen synthase kinase-3 (GSK-3) inhibitors
Inhibitors of CaMKIId
A VEGF inhibitor
JAK3 inhibitors
Inhibitors of NAD+-Dependent Histone Deacetylases
Inhibitors of human adipocyte fatty acid-binding protein
Cyclin-dependent kinase inhibitors

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H332-H335
• Precautionary statements: P261-P280-P305+P351+P338
• Hazard Codes: Xi
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29339900