5-Hydroxyindole-3-acetic Acid , ≥98% , 54-16-0

CAS NO.：54-16-0

Empirical Formula: C10H9NO3

Molecular Weight: 191.18

MDL number: MFCD00005639

EINECS: 200-195-4

PRODUCT Properties

• Melting point: 161-164 °C (dec.) (lit.)
• Boiling point: 326.92°C (rough estimate)
• Density: 1.2722 (rough estimate)
• refractive index: 1.5310 (estimate)
• storage temp.: -20°C
• solubility: Soluble in ethanol (50 mg/ml).
• pka: 4.54±0.30(Predicted)
• form: crystalline
• color: off-white to purple
• Sensitive: Light Sensitive
• BRN: 168797
• Stability: Air Sensitive, Light Sensitive
• InChIKey: DUUGKQCEGZLZNO-UHFFFAOYSA-N
• CAS DataBase Reference: 54-16-0

Description and Uses

5-hydroxy Indole-3-acetic acid (5-HIAA) is the primary metabolite of serotonin (5-HT; ). It is formed when 5-HT is metabolized by monamine oxidase and aldehyde dehydrogenase in the liver. 5-HIAA is excreted in urine and has been used as a biomarker for detection of neuroendocrine tumors and an internal standard for the quantification of serotonin metabolism in rat brain using mass spectrometry. 5-HIAA has also been associated with autism, insomnia, and chronic migraine.

5-Hydroxyindole-3-acetic acid is a major serotonin metabolite.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: NL3650000
• F: 8-10-23
• HS Code: 29339980