GW0742 , 98% , 317318-84-6

Synonym(s):
4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid

CAS NO.：317318-84-6

Empirical Formula: C21H17F4NO3S2

Molecular Weight: 471.49

MDL number: MFCD07369423

EINECS: 1532714-185-1

PRODUCT Properties

• Melting point: 134.5-135.5 °C
• Boiling point: 591.5±60.0 °C(Predicted)
• Density: 1.46±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: >5 mg/mL
• form: solid
• pka: 3.17±0.10(Predicted)
• color: white
• InChI: InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
• InChIKey: HWVNEWGKWRGSRK-UHFFFAOYSA-N
• SMILES: C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C

Description and Uses

GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.

GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.

Safety

• WGK Germany: 3
• HS Code: 38220090