A0785512
A-205804 , ≥98% , 251992-66-2
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB327.20 | In Stock |
|
| 50MG | RMB1395.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 198-199℃ |
| Boiling point: | 581.3±45.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | ≥30 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH |
| form | powder to crystal |
| pka | 15.12±0.30(Predicted) |
| color | White to Orange to Green |
Description and Uses
A-205804 is a potent inhibitor of E-selectin and ICAM-1 expression in human vascular endothelial cells stimulated with TNF-α (IC50s = 20 and 25 nM, respectively). It does not block expression of VCAM-1 (IC50 > 1,000 nM).
4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide is a reagent used in the preparation of selective inhibitors of cell adhesion molecule expression in human endothelial cells.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2934.99.9001 |
