3-ethynylimidazo[1,2-b]pyridazine , 97% , 943320-61-4

CAS NO.：943320-61-4

Empirical Formula: C8H5N3

Molecular Weight: 143.15

MDL number: MFCD17012027

PRODUCT Properties

• Density: 1.15±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• pka: 3.71±0.30(Predicted)
• form: solid
• color: White to grey

Description and Uses

3-Ethynylimidazo[1,2-b]pyridazine is used as an intermediate of Ponatinib, a BCR-ABL tyrosine kinase inhibitor anticancer drug used in the treatment of chronic myeloid leukaemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2933998090