3-Bromoimidazo[1,2-<i>b</i>]pyridazine , >98.0% , 18087-73-5

CAS NO.：18087-73-5

Empirical Formula: C6H4BrN3

Molecular Weight: 198.02

MDL number: MFCD09757672

PRODUCT Properties

• Melting point: 148.0 to 152.0 °C
• Density: 1.89
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: powder to crystal
• pka: 2.35±0.30(Predicted)
• color: White to Light yellow
• CAS DataBase Reference: 18087-73-5

Description and Uses

3-Bromoimidazo[1,2-B]pyridazine is a pharmaceutical intermediate compound. It is used in the preparation of Ponatinib, a tyrosine kinase inhibitor (TKI), which is used in the treatment of chronic myeloid leukaemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H332-H335
• Precautionary statements: P280-P305+P351+P338-P310
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 24/25
• HS Code: 29339900