Ergocalciferol (D2) , 98% , 50-14-6

Synonym(s):
Ergocalciferol;Calciferol;Ercalciol;Ergosterol irradiated;Irradiated ergosterol

CAS NO.：50-14-6

Empirical Formula: C28H44O

Molecular Weight: 396.65

MDL number: MFCD00166988

EINECS: 200-014-9

PRODUCT Properties

• Melting point: 114-118 °C(lit.)
• alpha: 82 º (c=3, in acetone 25 ºC)
• Boiling point: 460.3°C (rough estimate)
• Density: 0.9784 (rough estimate)
• vapor pressure: 7 x l0^-7 Pa (20 °C), est.)
• refractive index: 1.5100 (estimate)
• Flash point: 14 °C
• storage temp.: -20°C
• solubility: H₂O: 200 mg/mL, clear to hazy
• form: powder
• pka: 14.74±0.20(Predicted)
• color: white to yellowish
• optical activity: [α]20/D +105±2°, c = 4% in ethanol
• Water Solubility: Soluble in ethanol, water, methanol, dimethylformamide, and dimethyl sulfoxide.
• Merck: 14,10018
• BRN: 1916682
• BCS Class: 3
• Stability: Light Sensitive
• InChIKey: MECHNRXZTMCUDQ-RKHKHRCZSA-N
• LogP: 10.440 (est)
• CAS DataBase Reference: 50-14-6(CAS DataBase Reference)
• NIST Chemistry Reference: Ergocalciferol(50-14-6)
• EPA Substance Registry System: Ergocalciferol (50-14-6)

Description and Uses

Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer and immunity. Vitamin D may be obtained from many dietary sources, including eggs and fish, and is synthesized in the skin by the conversion of 7-dehydrocholesterol to vitamin D₃ by ultraviolet light. Vitamin D₂ is produced in fungi, including yeast, and invertebrates from ergosterol in response to ultraviolet radiation. In vertebrates as well as host organisms, vitamin D₂ is metabolized first to 25-hydroxyvitamin D₂ and subsequently to the active 1,25-dihydroxyvitamin D₂. Differences in the metabolism and action of vitamin D₂ vs. vitamin D₃ in mammals is a current topic of research interest.

The synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. Commercial solutions are usually made with propylene glycol or sesame oil. Antirachitic

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301+H311-H330-H372
• Precautionary statements: P260-P264-P280-P302+P352+P312-P304+P340+P310-P314
• Hazard Codes: Xn,T+,T,F
• Risk Statements: 22-48/25-26-24/25-40-23/24/25-48/22-23-11-20
• Safety Statements: 28-36/37-45-28A-36-26-36/37/39-22-16-7
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: KE1050000
• F: 1-8-10
• TSCA: Yes
• HazardClass: 6.1(a)
• PackingGroup: II
• HS Code: 29362900
• Hazardous Substances Data: 50-14-6(Hazardous Substances Data)