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A0624012

Ascorbic acid , 99.99%metalsbasis , 50-81-7

Synonym(s):
Ascorbic Acid;Vitamin C;L(+)-Ascorbic Acid;LYAG;L-AA

CAS NO.:50-81-7

Empirical Formula: C6H8O6

Molecular Weight: 176.12

MDL number: MFCD03457784

EINECS: 200-066-2

Pack Size Price Stock Quantity
25g RMB36.00 In Stock
100G RMB96.80 In Stock
500G RMB356.80 In Stock
2.5kg RMB1436.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 190-194 °C (dec.)
alpha  20.5 º (c=10,H2O)
Boiling point: 227.71°C (rough estimate)
Density  1,65 g/cm3
FEMA  2109 | ASCORBIC ACID
refractive index  21 ° (C=10, H2O)
storage temp.  Store at +5°C to +30°C.
solubility  H2O: 50 mg/mL at 20 °C, clear, nearly colorless
pka 4.04, 11.7(at 25℃)
form  powder
color  white to slightly yellow
PH 3.59(1 mM solution);3.04(10 mM solution);2.53(100 mM solution);
Odor Odorless
PH Range 1 - 2.5
optical activity [α]25/D 19.0 to 23.0°, c = 10% in H2O
Odor Type green
Water Solubility  333 g/L (20 ºC)
Merck  14,830
BRN  84272
BCS Class 1
Stability: Stable. May be weakly light or air sensitive. Incompatible with oxidizing agents, alkalies, iron, copper.
InChIKey CIWBSHSKHKDKBQ-JLAZNSOCSA-N
LogP -1.85
CAS DataBase Reference 50-81-7(CAS DataBase Reference)
NIST Chemistry Reference L-Ascorbic acid(50-81-7)
EPA Substance Registry System Ascorbic acid (50-81-7)

Description and Uses

Ascorbic acid, a water-soluble dietary supplement, is consumed by humans more than any other supplement. The name ascorbic means antiscurvy and denotes the ability of ascorbic to combat this disease. Vitamin C is the l-enantiomer of ascorbic acid. Ascorbic acid deficiency in humans results in the body’s inability to synthesize collagen, which is the most abundant protein in vertebrates.

vitamin C is a well-known anti-oxidant. Its effect on free-radical formation when topically applied to the skin by means of a cream has not been clearly established. The effectiveness of topical applications has been questioned due to vitamin C’s instability (it reacts with water and degrades). Some forms are said to have better stability in water systems. Synthetic analogues such as magnesium ascorbyl phosphate are among those considered more effective, as they tend to be more stable. When evaluating its ability to fight free-radical damage in light of its synergistic effect with vitamin e, vitamin C shines. As vitamin e reacts with a free radical, it, in turn, is damaged by the free radical it is fighting. Vitamin C comes in to repair the free-radical damage in vitamin e, allowing e to continue with its free-radical scavenging duties. Past research has indicated that high concentrations of topically applied vitamin C are photoprotective, and apparently the vitamin preparation used in these studies resisted soap and water, washing, or rubbing for three days. More current research has indicated that vitamin C does add protection against uVB damage when combined with uVB sunscreen chemicals. This would lead one to conclude that in combination with conventional sunscreen agents, vitamin C may allow for longer-lasting, broader sun protection. Again, the synergy between vitamins C and e can yield even better results, as apparently a combination of both provides very good protection from uVB damage. However, vitamin C appears to be significantly better than e at protecting against uVA damage. A further conclusion is that the combination of vitamins C, e, and sunscreen offers greater protection than the sum of the protection offered by any of the three ingredients acting alone. Vitamin C also acts as a collagen biosynthesis regulator. It is known to control intercellular colloidal substances such as collagen, and when formulated into the proper vehicles, can have a skin-lightening effect. Vitamin C is said to be able to help the body fortify against infectious conditions by strengthening the immune system. There is some evidence (although debated) that vitamin C can pass through the layers of the skin and promote healing in tissue damaged by burns or injury. It is found, therefore, in burn ointments and creams used for abrasions. Vitamin C is also popular in anti-aging products. Current studies indicate possible anti-inflammatory properties as well.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H319
Precautionary statements  P210-P305+P351+P338-P370+P378
Hazard Codes 
Risk Statements 
Safety Statements  24/25-36-26
WGK Germany  1
RTECS  CI7650000
TSCA  Yes
HS Code  29362700
Hazardous Substances Data 50-81-7(Hazardous Substances Data)
Toxicity LD50 oral in rat: 11900mg/kg

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