Diamide , 97%（HPLC） , 10465-78-8

Synonym(s):
N,N,N′,N′-Tetramethylazodicarboxamide;1,1′-Azobis(N,N-dimethylformamide);Azodicarboxylic acid bis(dimethylamide);Diazenedicarboxylic acid bis(N,N-dimethylamide);TMAD

CAS NO.：10465-78-8

Empirical Formula: C6H12N4O2

Molecular Weight: 172.19

MDL number: MFCD00008318

EINECS: 233-951-7

PRODUCT Properties

• Melting point: 112 °C
• Boiling point: 220.4±23.0 °C(Predicted)
• Density: 1.13±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: soluble in Methanol
• form: crystalline
• pka: -0?+-.0.70(Predicted)
• color: yellow
• BRN: 1910409
• InChI: InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+
• InChIKey: VLSDXINSOMDCBK-BQYQJAHWSA-N
• SMILES: C(=O)(/N=N/C(=O)N(C)C)N(C)C

Description and Uses

Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: LQ1041000
• F: 4.10
• HS Code: 29270000