2-Deoxy-D-glucose , 98% , 154-17-6
Synonym(s):
2-Deoxy-D -arabinohexose;2-Deoxyglucose
CAS NO.：154-17-6
Empirical Formula: C6H12O5
Molecular Weight: 164.16
MDL number: MFCD00151328
EINECS: 205-823-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB47.20 | In Stock |
|
| 5G | RMB199.20 | In Stock |
|
| 25G | RMB843.20 | In Stock |
|
| 100g | RMB2479.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 146-147 °C(lit.) |
| alpha | 45.5 º (c=2, H2O) |
| Boiling point: | 211.61°C (rough estimate) |
| Density | 1.1738 (rough estimate) |
| refractive index | 46.5 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless to faintly yellow |
| pka | pK1:12.52 (25°C) |
| form | crystalline |
| color | white |
| optical activity | +38.5 → +45.9 |
| Water Solubility | Soluble in water. |
| Merck | 14,2904 |
| BRN | 1723331 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day. |
| InChIKey | PMMURAAUARKVCB-CEZCPVKQSA-N |
| LogP | -1.460 (est) |
| CAS DataBase Reference | 154-17-6(CAS DataBase Reference) |
| EPA Substance Registry System | D-arabino-Hexose, 2-deoxy- (154-17-6) |
Description and Uses
2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-Deoxy-D-glucose competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2
2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 24/25-37/39-36-26 |
| WGK Germany | 3 |
| RTECS | MQ3325000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29400090 |
| Hazardous Substances Data | 154-17-6(Hazardous Substances Data) |
