Home Categories 3,4-Dimethoxyphenethylamine
A3176612

3,4-Dimethoxyphenethylamine , 97% , 120-20-7

Synonym(s):
2-(3,4-Dimethoxyphenyl)ethylamine;Homoveratrylamine

CAS NO.:120-20-7

Empirical Formula: C10H15NO2

Molecular Weight: 181.23

MDL number: MFCD00008188

EINECS: 204-376-9

Pack Size Price Stock Quantity
5G RMB23.20 In Stock
25G RMB39.20 In Stock
100G RMB128.00 In Stock
500G RMB531.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 12-15 °C
Boiling point: 188 °C15 mm Hg(lit.)
Density  1.074 g/mL at 25 °C(lit.)
vapor pressure  0.348-0.348Pa at 25℃
refractive index  n20/D 1.546(lit.)
Flash point: >230 °F
storage temp.  Refrigerator
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 9.74±0.10(Predicted)
form  Viscous Liquid
Specific Gravity 1.10
color  Clear light yellow to orange or slightly brownish
PH 11.4 (100g/l, H2O, 20℃)
explosive limit 0.1-1.7%(V)
Water Solubility  SOLUBLE
Sensitive  Air Sensitive
InChIKey ANOUKFYBOAKOIR-UHFFFAOYSA-N
LogP 0.77
CAS DataBase Reference 120-20-7(CAS DataBase Reference)
NIST Chemistry Reference Benzeneethanamine, 3,4-dimethoxy-(120-20-7)
EPA Substance Registry System Benzeneethanamine, 3,4-dimethoxy- (120-20-7)

Description and Uses

3,4-Dimethoxyphenylethylamine, also known as 3,4-DMPEA or DMPEA is an endogenous metabolite found in urine that belongs to both the phenethylamine and catecholamine families. DMPEA is an analogue of dopamine (3,4-dihydroxyphenethylamine), with a substitution of the hydroxy groups with methoxy groups. It is also structurally similar to mescaline (3,4,5-trimethoxyphenylethylamine) and occurs naturally alongside it in various species of cacti such as the San Pedro and Peruvian Torch. DMPEA received wide attention after it was proposed as a biomarker in schizophrenic patients urine, however later studies revealed that DMPEA is also excreted by non-schizophrenics. DMPEA has little known bioactivity, but it has some action as a monoamine oxidase inhibitor. It has also been shown to have neurotoxic effects, especially in the nigrostriatal system and among dopaminergic neurons. DMPEA appears to be an inhibitor of mitochondrial complex I.

3,4-Dimethoxyphenethylamine is a methylated metabolite of Dopamine (D533780); a potent inhibitor of brain mitochondrial respiration used in Parkinson’s disease studies.

Safety

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H317-H318
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
RIDADR  UN 2735
WGK Germany  3
RTECS  SH2300000
10
Hazard Note  Irritant
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29222900
Toxicity mouse,LD50,intraperitoneal,181mg/kg (181mg/kg),Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.

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