1-Deoxynojirimycin , Analysis of standard products, ≥98% , 19130-96-2

Synonym(s):
1,5-Dideoxy-1,5-imino-D-sorbitol;DNM;DNM1

CAS NO.：19130-96-2

Empirical Formula: C6H13NO4

Molecular Weight: 163.17

MDL number: MFCD00063474

EINECS: 606-239-2

PRODUCT Properties

• Melting point: 195-196°C
• Boiling point: 361.1±42.0 °C(Predicted)
• Density: 1.456±0.06 g/cm3(Predicted)
• vapor pressure: 0Pa at 25℃
• RTECS: TN4350300
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: Soluble in Water up to 25 mg/ml).
• pka: 13.77±0.70(Predicted)
• form: Powder
• color: White
• Water Solubility: Soluble in water, dimethyl sulfoxide and methanol.
• BRN: 3588039
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
• LogP: -1.8
• CAS DataBase Reference: 19130-96-2(CAS DataBase Reference)

Description and Uses

Deoxynojirimycin (19130-96-2) inhibits α-glucosidase I and II.1,2 Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step.3 May be used to produce an affinity ligand for purifying glucosidase 1.4 Deoxynojirimycin was used to inhibit ER glucosidases I and II allowing for the discovery of a second mechanism for deglucosylation of N-linked oligosaccharides in PhaR1.7, a mouse lymphoma cell line.5

Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P271-P280
• Safety Statements: 24/25
• WGK Germany: 1
• HS Code: 29329990