2-Chloro-6-methylpyridine , 98% , 18368-63-3

Synonym(s):
6-Chloro-2-picoline

CAS NO.：18368-63-3

Empirical Formula: C6H6ClN

Molecular Weight: 127.57

MDL number: MFCD00006245

EINECS: 242-241-6

PRODUCT Properties

• Boiling point: 64-68 °C10 mm Hg(lit.)
• Density: 1.167 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.527(lit.)
• Flash point: 165 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: Liquid
• pka: 1.10±0.10(Predicted)
• color: Clear colorless to light yellow
• Specific Gravity: 1.167
• BRN: 107187
• InChI: InChI=1S/C6H6ClN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3
• InChIKey: GXZDYRYYNXYPMQ-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC(C)=CC=C1
• CAS DataBase Reference: 18368-63-3(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cl-6-(CH3)-pyridine(18368-63-3)
• EPA Substance Registry System: Pyridine, 2-chloro-6-methyl- (18368-63-3)

Description and Uses

2-Chloro-6-methylpyridine (2C6MP) is a strong inhibitor of methane monooxygenase, a key enzyme in the aerobic oxidation of methane (CH4). It belongs to the pesticide nitropyridine group of compounds. Studies have shown that 2C6MP has the least effect on CH4 oxidation at concentrations of 0.1 mM and 1 mM, but at a concentration of 10 mM, 2C6MP inhibits CH4 oxidation for >20 months. Low concentrations of 2C6MP did not inhibit Methylophilaceae, while high concentrations of 2C6MP inhibited Methylophilaceae by only 7.8 ± 1.1%^[1].

2-Chloro-6-methylpyridine has been used for experimental FTIR and FT-Raman spectroscopic analyses, as well as for conformational studies.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P302+P352-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• RIDADR: UN2810
• WGK Germany: 3
• Hazard Note: Irritant
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29333990