A2312912
4-(Chloromethyl)pyridine hydrochloride , 97% , 1822-51-1
Synonym(s):
4-Picolyl chloride hydrochloride
CAS NO.:1822-51-1
Empirical Formula: C6H7Cl2N
Molecular Weight: 164.03
MDL number: MFCD00012826
EINECS: 217-350-7
Pack Size | Price | Stock | Quantity |
5G | RMB25.60 | In Stock |
|
25G | RMB43.20 | In Stock |
|
100G | RMB168.80 | In Stock |
|
500g | RMB702.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 166-173 °C(lit.) |
storage temp. | Inert atmosphere,2-8°C |
solubility | soluble in DMSO, Methanol |
form | Fine Crystalline Powder |
color | Yellow to orange |
Water Solubility | 750 g/L (20 ºC) |
Sensitive | Hygroscopic |
BRN | 3689154 |
CAS DataBase Reference | 1822-51-1(CAS DataBase Reference) |
Description and Uses
It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst?15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Safety
Symbol(GHS) | GHS05 |
Signal word | Danger |
Hazard statements | H314 |
Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 |
Hazard Codes | C,Xi |
Risk Statements | 34-4-22-36/37/38 |
Safety Statements | 26-36/37/39-45-36 |
RIDADR | UN 3261 8/PG 3 |
WGK Germany | 3 |
F | 3-10 |
Hazard Note | Corrosive |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29333999 |