N-Chlorosuccinimide , 98% , 128-09-6

Synonym(s):
1-Chloro-2,5-pyrrolidinedione;N-Chlorosuccinimide;NCS;NCS, Succinchlorimide

CAS NO.：128-09-6

Empirical Formula: C4H4ClNO2

Molecular Weight: 133.53

MDL number: MFCD00005511

EINECS: 204-878-8

PRODUCT Properties

• Melting point: 148-150 °C (lit.)
• Density: 1,65 g/cm³
• vapor pressure: 1.04Pa at 25℃
• refractive index: 1.4378 (estimate)
• Flash point: >110°C
• storage temp.: Store at +2°C to +8°C.
• solubility: 14g/l
• form: Crystalline Powder
• pka: -2.78±0.20(Predicted)
• color: White
• Odor: chlorine odor
• Water Solubility: Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
• Sensitive: Moisture Sensitive
• Merck: 14,2164
• BRN: 113915
• Boiling point: 216.5°C
• InChIKey: JRNVZBWKYDBUCA-UHFFFAOYSA-N
• LogP: -1.19

Description and Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Safety

• Symbol(GHS): GHS05,GHS07,GHS09
• Signal word: Danger
• Hazard statements: H290-H302-H314-H335-H410
• Precautionary statements: P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338
• Hazard Codes: C,Xi
• Risk Statements: 22-34
• Safety Statements: 26-36/37/39-45-37/39
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• RTECS: UY1013500
• F: 21
• Hazard Note: Irritant
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• HS Code: 29251995
• Toxicity: MLD orally in rats: 2.7 g/kg (Stohlman, Smith)