Cytochalasin D , 98% , 22144-77-0

Synonym(s):
Cytochalasin D, Zygosporium mansonii - CAS 22144-77-0 - Calbiochem;InSolution Cytochalasin D, Zygosporium mansonii - CAS 22144-77-0 - Calbiochem;Lygosporin A, Zygosporin A, NSC 209835;Zygosporin A

CAS NO.：22144-77-0

Empirical Formula: C30H37NO6

Molecular Weight: 507.62

MDL number: MFCD00077706

EINECS: 244-804-1

PRODUCT Properties

• Melting point: 255-260°C
• Boiling point: 595.84°C (rough estimate)
• Density: 1.1764 (rough estimate)
• refractive index: 1.6310 (estimate)
• Flash point: 87℃
• storage temp.: −20°C
• solubility: DMSO: soluble
• pka: 11.95±0.70(Predicted)
• form: White solid
• color: White
• BRN: 1632828
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
• LogP: 2.640 (est)
• EPA Substance Registry System: Cytochalasin D (22144-77-0)

Description and Uses

Cytochalasin D (22144-77-0) is a potent inhibitor of actin polymerization which also causes the disruption of actin filaments. More potent that cytochalasin B (10-fold) and does not inhibit monosaccharide transport across cell membranes. Disruption of actin microfilaments leads to activation of p53. Cell permeable

A cell cycle arresting compound used in actin polymerization studies and cytological research

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H300
• Precautionary statements: P264-P270-P301+P310-P405-P501
• Hazard Codes: T
• Risk Statements: 25-63
• Safety Statements: 36/37-45
• RIDADR: UN 1544 6.1/PG 2
• WGK Germany: 3
• RTECS: GZ4850000
• HazardClass: 6.1(a)
• PackingGroup: I
• HS Code: 29337900
• Hazardous Substances Data: 22144-77-0(Hazardous Substances Data)