2-<WBR>[2-<WBR>(Boc-<WBR>amino)<WBR>ethoxy]<WBR>ethanol , 97% , 139115-91-6

Synonym(s):
[2-(2-Hydroxyethoxy)ethyl]carbamic acid 1,1-dimethylethyl ester;N-[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester;tert-Butyl[2-(2-hydroxyethoxy)ethyl]carbamate;2-(2-tert-Butoxycarbonylaminoethoxy)ethanol

CAS NO.：139115-91-6

Empirical Formula: C9H19NO4

Molecular Weight: 205.25

MDL number: MFCD04038542

PRODUCT Properties

• Boiling point: 332.9±22.0 °C(Predicted)
• Density: 1.061 g/mL at 25 °C
• refractive index: n20/D1.454
• Flash point: >110℃
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• form: clear liquid
• pka: 12.20±0.46(Predicted)
• color: Colorless to Light orange to Yellow

Description and Uses

N-Boc-PEG2-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

2-[2-(Boc-amino)ethoxy]ethanol is N-terminal protected 2-(2-aminoethoxy)ethanol. It is generally used as a molecular spacer/linker. Some of such applications are:

• Synthesis of biotinylated HaloLigands to prepare quantum dot adducts for HaloTag protein-mediated specific labeling of live cells.
• It is one of the key precursors for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagent used for identification of tyroscherin binding proteins.
• It can be used to link HaloTag enzyme with fluorescent zinc indicator, ZIMIR to monitor the dynamics of regulated secretion of zinc in real time.
• It can also be used to synthesize amphiphiles for DNA and siRNA delivery.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H319
• Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25-36-37-38
• Safety Statements: 36/39-45
• RIDADR: 2810
• WGK Germany: 3
• HS Code: 2924.19.8000
• HazardClass: 6.1
• PackingGroup: Ⅲ