betamethasone 21-phosphate sodium , ≥97% , 151-73-5

Synonym(s):
Betamethasone 21-phosphate disodium;Betamethasone disodium phosphate;Betamethasone sodium phosphate

CAS NO.：151-73-5

Empirical Formula: C22H28FNa2O8P

Molecular Weight: 516.4

MDL number: MFCD00200361

EINECS: 205-797-0

PRODUCT Properties

• Melting point: 206-211°C
• alpha: +98.0～+104.0°(D/20℃)(c=1,H2O) (calculated on the dehydrous basis)
• storage temp.: room temp
• solubility: Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
• form: Solid
• color: White to Off-White
• PH: 7.5～9.0(5g/l, 25℃)
• Merck: 14,1180
• Stability: Hygroscopic
• InChIKey: PLCQGRYPOISRTQ-LWCNAHDDSA-L
• SMILES: [C@@]12([H])C[C@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r|

Description and Uses

Betamethasone 21-Phosphate Disodium Salt (Dexamethasone Sodium Phosphate EP Impurity B) is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360FD-H373
• Precautionary statements: P202-P260-P264-P270-P301+P312-P308+P313
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: TU4056500
• HS Code: 29372290
• Toxicity: LD50 orl-rat: 1877 mg/kg DRUGAY -,1075,90