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A1424150

17a-Hydroxyprogesteronecaproate , 98% , 630-56-8

Synonym(s):
17α-Hydroxyprogesterone caproate;17α-Hydroxyprogesterone hexanoate

CAS NO.:630-56-8

Empirical Formula: C27H40O4

Molecular Weight: 428.6

MDL number: MFCD00072134

EINECS: 211-138-8

Pack Size Price Stock Quantity
1g RMB148.00 In Stock
5g RMB400.80 In Stock
25g RMB1201.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 119°C
Boiling point: 463.43°C (rough estimate)
alpha  +44~+50°(D/20℃)(c=1,CH3OH)
Density  1.0148 (rough estimate)
refractive index  1.4840 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  Off-White
Merck  4839
InChIKey DOMWKUIIPQCAJU-LJHIYBGHSA-N
SMILES C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(=O)CCCCC)(C(=O)C)CC3)CC2

Description and Uses

Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999. The U.S. FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy.

Hydroxyprogesterone Caproate is a synthetic progestin that reduces the chances of pre-term birth in women and improves specific fetal outcomes.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Risk Statements  61
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  TU5085000
HS Code  2937230000

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