Bromhexine HCl , ≥98% , 611-75-6

Synonym(s):
N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride;2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride;Bromhexine hydrochloride;Bromohexine hydrochloride

CAS NO.：611-75-6

Empirical Formula: C14H21Br2ClN2

Molecular Weight: 412.59

MDL number: MFCD00056626

EINECS: 210-280-8

PRODUCT Properties

• Melting point: 240-244 °C
• storage temp.: Sealed in dry,Room Temperature
• solubility: Very slightly soluble in water, slightly soluble in alcohol and in methylene chloride.
• form: powder
• color: White to Light Beige
• λmax: 307nm(Decane)(lit.)
• Merck: 14,1391
• BRN: 4848376
• InChIKey: UCDKONUHZNTQPY-UHFFFAOYSA-N
• LogP: 5.081 (est)
• CAS DataBase Reference: 611-75-6(CAS DataBase Reference)

Description and Uses

Bromhexine Hydrochloride is the hydrochloride salt form of bromhexine, a secretolytic, with mucolytic activity. Upon administration, bromhexine increases lysosomal activity and enhances hydrolysis of acid mucopolysaccharide polymers in the respiratory tract. This increases the production of serous mucus in the respiratory tract, which makes the phlegm thinner and decreases mucus viscosity. This contributes to its secretomotoric effect, and allows the cilia to more easily transport the phlegm out of the lungs. This clears mucus from the respiratory tract and may aid in the treatment of respiratory disorders associated with abnormal viscid mucus, excessive mucus secretion and impaired mucus transport.

Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 2
• RTECS: XS9950000
• HS Code: 29215990