Home Categories Biochemical Engineering WH-4-023
A1256350

WH-4-023 , ≥98%(HPLC) , 837422-57-8

Synonym(s):
2,6-Dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate;KIN112

CAS NO.:837422-57-8

Empirical Formula: C32H36N6O4

Molecular Weight: 568.67

MDL number: MFCD28138072

Pack Size Price Stock Quantity
5mg RMB319.20 In Stock
10mg RMB503.20 In Stock
25mg RMB999.20 In Stock
50mg RMB1425.60 In Stock
100mg RMB2719.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 743.2±70.0 °C(Predicted)
Density  1.247±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in DMSO (60 mg/ml)
pka 7.89±0.42(Predicted)
form  powder
color  white to beige
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.

Description and Uses

WH-4-23 (837422-57-8) is a potent and selective inhibitor of Src family kinases Lck and Src, IC50=2 and 6 nM respectively.1,2 Also inhibits SIK, IC50=10, 22 and 60 nM for SIK 1, 2 and 3 respectively.3 May be used along with PD-325901 and CHIR-99021 to support self-renewal of na?ve human embryonic stem cells.4

WH-4-023 is a potent and selective dual lymphocyte-specific kinase (Lck) inhibitor.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P405-P501
RIDADR  UN 2811 6.1 / PGIII

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