A1225712
Boc-Pro-OH , 99% , 15761-39-4
Synonym(s):
N-(tert-Butoxycarbonyl)-L -proline;Boc-L -proline;Boc-Pro-OH;N-α-t.-Boc-L-proline
CAS NO.:15761-39-4
Empirical Formula: C10H17NO4
Molecular Weight: 215.25
MDL number: MFCD00037324
EINECS: 239-848-3
Pack Size | Price | Stock | Quantity |
5G | RMB23.20 | In Stock |
|
25G | RMB40.80 | In Stock |
|
100G | RMB119.20 | In Stock |
|
500G | RMB543.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 133-135 °C(lit.) |
alpha | -60.5 º (c=1, HAc) |
Boiling point: | 355.52°C (rough estimate) |
Density | 1.1835 (rough estimate) |
refractive index | -60 ° (C=2, AcOH) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in acetic acid. |
form | Crystals or Crystalline Powder |
pka | 4.01±0.20(Predicted) |
color | White |
optical activity | [α]20/D 61±2°, c = 2% in acetic acid |
BRN | 15828 |
InChIKey | ZQEBQGAAWMOMAI-ZETCQYMHSA-N |
CAS DataBase Reference | 15761-39-4(CAS DataBase Reference) |
EPA Substance Registry System | 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- (15761-39-4) |
Description and Uses
N-Boc-L-proline is a synthetic intermediate. It has been used in the synthesis of enantioselective catalysts for aldol reactions and hepatitis C virus (HCV) NS5A inhibitors.
N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 2933 99 80 |
HazardClass | IRRITANT |