Home Categories Biochemical Engineering Cis-4-Hydroxy-L-proline
A4722112

Cis-4-Hydroxy-L-proline , 98% , 618-27-9

Synonym(s):
(2S,4S)-(−)-4-Hydroxy-2-pyrrolidinecarboxylic acid;CHP

CAS NO.:618-27-9

Empirical Formula: C5H9NO3

Molecular Weight: 131.13

MDL number: MFCD00064319

EINECS: 210-542-1

Pack Size Price Stock Quantity
50MG RMB28.00 In Stock
250MG RMB58.40 In Stock
1G RMB133.60 In Stock
5g RMB388.80 In Stock
25g RMB1236.00 In Stock
100g RMB5039.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 257 °C (dec.) (lit.)
alpha  -59 º (c=2, H2O)
Boiling point: 242.42°C (rough estimate)
Density  1.3121 (rough estimate)
refractive index  -59 ° (C=2, H2O)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  soluble
form  Powder
pka 2.14±0.40(Predicted)
color  White to beige
Water Solubility  soluble
Merck  14,4840
BRN  81440
InChIKey PMMYEEVYMWASQN-IMJSIDKUSA-N

Description and Uses

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line and rat pancreatic carcinoma cell line DSL6A.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36/37/39-27-26
WGK Germany  3
10
TSCA  Yes
HS Code  29339900

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